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Case Reports • An. Bras. Dermatol. 94 (5) • Nov-Dec 2019 • https://doi.org/10.1016/j.abd.2019.09.014   copy

Chromoblastomycosis caused by Rhinocladiella aquaspersa: first case report in Guatemala☆ ☆ How to cite this article: Porras-López C, Frías-De-León MG, Arenas R, Martínez-Herrera E. Chromoblastomycosis caused by Rhinocladiella aquaspersa: first case report in Guatemala. An Bras Dermatol. 2019;94:574-7. ☆☆ ☆☆ Study conducted at the Hospital Regional de Alta Especialidad de Ixtapaluca, Ixtapaluca, Mexico.

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Abstract

The authors report a case of 40-year-old male patient with a five-year history of chromoblastomycosis on his right leg. Diagnosis was performed by direct 40% KOH exam of skin scales, culture with micro- and macromorphologic analysis, and genotypic characterization (sequencing of a fragment of the ITS region and phylogenetic analysis) of the isolated fungus. Rhinocladiella aquaspersa was identified as the etiological agent. Initially, the treatment was with oral itraconazole 200 mg/day for one year. However, the presence of “sclerotic cells” with filaments (“Borelli spiders”) resulted in a change of medical treatment: a higher dose of itraconazole (400 mg/day) and surgery, achieving clinical and mycological cure in one year. This is the first report of chromoblastomycosis caused by R. aquaspersa in Guatemala.

KEYWORDS
Chromoblastomycosis; Dermatology; Mycoses

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