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Therapeutic cyanoacrylate glue for corneal perforations

Purpose: To investigate the indications, outcomes and complications of cyanoacrylate tissue adhesive for stromal thinning and corneal perforations. Methods: Twenty-six eyes of 26 patients with stromal thinning or corneal perforations (£ 2.5 mm) received methyl 2-cya-noacrylate adhesive and bandage contact lens. Results: Twelve cases (46%) of corneal perforation were caused by infectious ulcer. For the 26 eyes that received adhesive, 15 (57.7%) needed only one application of the glue and 11 (42.3%) needed two applications. Thirteen eyes (50%) developed for leukoma; 4 (15%) needed surgery and 9 (35%) eyes remained sealed. Visual acuity remained unaltered in 15 eyes (57.7%), improved in 7 (27%) and got worse in 4 (15.3%) eyes. Conclusion: The cyanoacrylate adhesive is available to all ophthalmologists and is an effective method of temporary or permanent closure of an impending or frank perforation.

Cornea; perforations; adhesive


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