Results evaluation of the use of intra-articular sodium
               hyaluronate in the post-operative knee arthroscopy<sup>,</sup>

Pereira Junior, Ayrton de Paula; Fasolin, Ricardo Pozzi; Sossa, Felipe Ayusso Correa; Lira Neto, Ozorio de Almeida; Navarro, Marcelo Schmidt; Milani, Antonio

doi:10.1016/j.rbo.2012.12.002

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• Rev. bras. ortop. 49 (1) • Jan-Feb 2014 • https://doi.org/10.1016/j.rboe.2014.01.005 copy

Results evaluation of the use of intra-articular sodium hyaluronate in the post-operative knee arthroscopy^☆ ☆ Please cite this article as: de Paula Pereira Junior A, Fasolin RP, Sossa FAC, de Almeida Lira Neto O, Navarro MS, Milani A. Avaliação dos resultados do uso do hialuronato de sódio intra-articular no pós-operatório da artroscopia do joelho. Rev Bras Ortop. 2014;49:37–43. ^,^☆☆ ☆☆ Study conducted at the Hospital Ifor, São Bernardo do Campo, SP, Brazil.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Objective:

to evaluate the efficacy of hyaluronic acid in the post-operative of knee arthroscopy.

Methods:

we have evaluated 49 patients undergoing arthroscopic procedure with the use of intra-articular hyaluronic acid (Group 1) and 49 patients undergoing arthroscopic procedure without the use of hyaluronic acid (Group 2). Patients were evaluated based on the Visual Analogue Scale, household analgesia, assessment of the Range of Motion with a goniometer, and the Lysholm questionnaire.

Results:

there were no substantial adverse effects on either group.

Conclusion:

the use of hyaluronic acid in the post-operative of knee arthroscopy is justified due/because it leads to a decrease in pain in the early stage, enabling faster recovery of the patient.

Arthroscopy; Knee; Hyaluronic acid; Viscosuplementation

Variables		n = 98	Group 1 = 49	Group 2 = 49
Age (years) - mean (SD)		34 (12.1)	36 (11.3)	33 (12.1)
Minimum-maximum		18-65	20-65	18-61
Gender - n (%)
	Female	33 (37)	15 (30.6)	18 (36.7)
	Male	65 (63)	34 (69.4)	31 (63.3)
Operated site - n (%)
	Right	58 (59.2)	26 (53)	32 (65.3)
	Left	40 (40.8)	23 (47)	17 (34.7)
Chondral lesion^a a Outerbridge. - n (%)
	Without lesion	43 (43.9)	22 (44.9)	21 (42.9)
	Grade I	31 (31.6)	14 (28.6)	17 (34.7)
	Grade II	24 (24.5)	13 (26.5)	11 (22.4)

Group/time point	Comparison	Mean estimated difference	Standard error	t value	gL	p
Group 1	3 days-8 days	3.86	0.10	38.60	384	<0.001
	3 days-15 days	5.20	0.13	41.05	384	<0.001
	3 days-30 days	6.22	0.14	44.25	384	<0.001
	3 days-60 days	7.02	0.15	47.27	384	<0.001
	8 days-15 days	1.35	0.10	13.48	384	<0.001
	8 days-30 days	2.37	0.13	18.67	384	<0.001
	8 days-60 days	3.16	0.14	22.49	384	<0.001
	15 days-30 days	1.02	0.10	10.21	384	<0.001
	15 days-60 days	1.82	0.13	14.33	384	<0.001
	30 days-60 days	0.80	0.10	7.97	384	<0.001
Group 2	3 days-8 days	2.27	0.10	22.67	384	<0.001
	3 days-15 days	4.33	0.13	34.12	384	<0.001
	3 days-30 days	6.37	0.14	45.26	384	<0.001
	3 days-60 days	7.06	0.15	47.55	384	<0.001
	8 days-15 days	2.06	0.10	20.63	384	<0.001
	8 days-30 days	4.10	0.13	32.35	384	<0.001
	8 days-60 days	4.80	0.14	34.09	384	<0.001
	15 days-30 days	2.04	0.10	20.42	384	<0.001
	15 days-60 days	2.73	0.13	21.57	384	<0.001
	30 days-60 days	0.69	0.10	6.94	384	<0.001
3 days	Group 1-Group 2	-0.10	0.16	-0.64	384	>0.999
8 days	Group 1-Group 2	-1.69	0.16	-10.59	384	<0.001
15 days	Group 1-Group 2	-0.98	0.16	-6.12	384	<0.001
30 days	Group 1-Group 2	0.04	0.16	0.26	384	>0.999
60 days	Group 1-Group 2	-0.06	0.16	-0.38	384	>0.999

Group/time point	Comparison	Mean estimated difference	Standard error	t value	gL	p
Group 1	Pre-15 days	1.10	0.28	3.92	288	0.003
	Pre-30 days	-43.47	0.33	-133.55	288	<0.001
	Pre-60 days	-47.76	0.34	-140.79	288	<0.001
	15 days-30 days	-44.57	0.28	-158.49	288	<0.001
	15 days-60 days	-48.86	0.33	-150.11	288	<0.001
	30 days-60 days	-4.29	0.28	-15.24	288	<0.001
Group 2	Pre-15 days	12.02	0.28	42.74	288	<0.001
	Pre-30 days	-28.88	0.33	-88.72	288	<0.001
	Pre-60 days	-41.84	0.34	-123.34	288	<0.001
	15 days-30 days	-40.90	0.28	-145.43	288	<0.001
	15 days-60 days	-53.86	0.33	-165.47	288	<0.001
	30 days-60 days	-12.96	0.28	-46.08	288	<0.001
Pre	Group 1-Group 2	-1.73	0.35	-5.01	288	<0.001
15 days	Group 1-Group 2	9.18	0.35	26.54	288	<0.001
30 days	Group 1-Group 2	12.86	0.35	37.16	288	<0.001
60 days	Group 1-Group 2	4.18	0.35	12.09	288	<0.001

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