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Case Report • Rev. Soc. Bras. Med. Trop. 56 • 2023 • https://doi.org/10.1590/0037-8682-0007-2023   copy

Cogan’s sign in a patient with suspected post-COVID-19 vaccine-associated myasthenia gravis

Authorship SCIMAGO INSTITUTIONS RANKINGS

ABSTRACT

The Cogan’s sign is indicative of myasthenia gravis. This is the first report of neurological signs in a patient with post-COVID-19 vaccine-associated myasthenia gravis in Brazil. In this case, a previously healthy 68-year-old woman presented with proximal limb weakness, left ptosis, and diplopia 1 month after receiving her fourth dose of the COVID-19 vaccine. Neurological examination revealed the presence of Cogan’s sign, and she recovered rapidly after treatment. To our knowledge, this is the first reported case of myasthenia gravis associated with the COVID-19 vaccine in Brazil.

Keywords:
COVID-19; SARS-CoV-2 Infection; Myasthenia Gravis

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