ABSTRACT
Background:
The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil.
Methods:
Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status.
Results:
None of the study sites had significantly higher POC-ECO accuracy than KK.
Conclusions:
POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs.
Keywords:
Schistosoma mansoni; Point-of-care (POC); Circulating cathodic antigen (CCA); Kato-Katz; Helmintex; Brazil