Zheng et al.,((88 Zheng F, Liao C, Fan Q, Chen H, Zhao X, Xie Z, et al. Clinical characteristics of children with Coronavirus Disease 2019 in Hubei, China. Curr Med Sci. 2020;40(2):1-6. doi: 10.1007/s11596-020-2172-6 https://doi.org/10.1007/s11596-020-2172-...
))
|
0 - 6y |
Travel history |
Suspected hereditary metabolic diseases and congenital heart disease |
Yes/10 |
Dong et al.,((1111 Dong N, Cai J, Zhou Y, Liu J, Li F. End-stage Heart Failure with COVID-19: strong evidence of myocardial injury by 2019-nCoV. JACC: Heart Failure. 2020. doi: 10.1016/j.jchf.2020.04.001 https://doi.org/10.1016/j.jchf.2020.04.0...
))
|
11y |
NS |
Heart failure |
Yes/NS |
Escalera-Antezana et al.,((1212 Escalera-Antezana JP, Lizon-Ferrufino NF, Maldonado-Alanoca A, Alarcón-De-la-Vega G, Alvarado-Arnez LE, Balderrama-Saavedra MA, et al. Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain. Travel Med Infect Dis. 2020. doi: 10.1016/j.tmaid.2020.101653 https://doi.org/10.1016/j.tmaid.2020.101...
))
|
13 and 18y |
Family transmission and NS |
No |
No |
Díaz et al.,((1313 Díaz CA, Maestro ML, Pumarega MTM, Antón BF, Alonso CRP. Primer caso de infección neonatal por SARS-CoV-2 en España. An Pediatr. 2020;92(4):237-8. doi: 10.1016/j.anpedi.2020.03.002 https://doi.org/10.1016/j.anpedi.2020.03...
))
|
8d |
Community transmission |
Prematurity |
Yes/13 |
Chen et al.,((1414 Chen C, Gao G, Xu Y, Pu L, Wang Q, Wang L, et al. SARS-CoV-2-Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19. Ann Intern Med. 2020;M20-0991. doi: 10.7326/M20-0991 https://doi.org/10.7326/M20-0991...
))
|
2 - 10y |
Community transmission |
No |
Yes/NS |
Xiang et al.,((1515 Xiang M, Liang S, Zhang Y, Zhang X, Gai Z, Zhang Z. Do children need a longer time to shed SARS-CoV-2 in stool than adults? J Microbiol, Immunol Infect. 2020. doi: 10.1016/j.jmii.2020.03.010 https://doi.org/10.1016/j.jmii.2020.03.0...
))
|
11m -9y |
Family transmission |
NS |
Yes/NS |
Peng e Zhang((1616 Peng A, Zhang M. Novel coronavirus SARS-CoV-2: familial spread resulting in COVID-19 pneumonia in a pediatric patient. Diagn Interv Radiol. 2020;26(3):262-3. doi: 10.5152/dir.2020.20157 https://doi.org/10.5152/dir.2020.20157...
))
|
03y |
Family transmission |
No |
NS |
Park et al.((1717 Park JY, Han MS, Park KU, Kim JY, Choi EH. First Pediatric Case of Coronavirus Disease 2019 in Korea. J Korean Med Sci. 2020;35(11):e124. doi: 10.3346/jkms.2020.35.e124 https://doi.org/10.3346/jkms.2020.35.e12...
))
|
10y |
Family transmission |
No |
Yes/15 |
Lu et al.((1818 Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. New England J Med. 2020;382(17):1663-5. doi: 10.1056/NEJMc2005073 https://doi.org/10.1056/NEJMc2005073...
))
|
0 - 16y |
Family transmission |
Hydronephrosis and leukemia |
NS |
Ng et al.((1919 Ng O-T, Marimuthu K, Chia P-Y, Koh V, Chiew CJ, De Wang L, et al. SARS-CoV-2 Infection among Travelers Returning from Wuhan, China. N Engl J Med. 2020;382(15):1476-8. doi: 10.1056/NEJMc2003100 https://doi.org/10.1056/NEJMc2003100...
))
|
17y |
Community transmission |
No |
No |
Wang et al.((2020 Wang S, Guo L, Chen L, Liu W, Cao Y, Zhang J, et al. A case report of neonatal COVID-19 infection in China. Clin Infect Dis. 2020. doi: 10.1093/cid/ciaa225 https://doi.org/10.1093/cid/ciaa225...
))
|
36h |
Vertical transmission |
No |
Yes/18 |
Cao et al.((2121 Cao Q, Chen Y-C, Chen C-L, Chiu C-H. SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics. J Formosan Med Assoc. 2020;119(3):670-3. doi: 10.1016/j.jfma.2020.02.009 https://doi.org/10.1016/j.jfma.2020.02.0...
))
|
03m |
Family transmission |
No |
Yes/15 |
Guan et al.((2222 Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708-20. doi: 10.1056/NEJMoa2002032 https://doi.org/10.1056/NEJMoa2002032...
))
|
0 - 15y |
Community transmission |
No |
NS |
Mansour et al.,((2323 Mansour A, Atoui R, Kanso K, Mohsen R, Fares Y, Fares J. First Case of an Infant with COVID-19 in the Middle East. Cureus. 2020. doi: 10.7759/cureus.7520 https://doi.org/10.7759/cureus.7520...
))
|
16m |
Family transmission |
Infection for Streptococcus pneumoniae
|
Yes/NS |
Pan et al.((2424 Pan X, Chen D, Xia Y, Wu X, Li T, Ou X, et al. Asymptomatic cases in a family cluster with SARS-CoV-2 infection. Lancet Infect Dis. 2020;20(4):410-1. doi: 10.1016/S1473-3099(20)30114-6 https://doi.org/10.1016/S1473-3099(20)30...
))
|
03y |
Family transmission |
No |
Yes/03 |
Sun et al.((2525 Sun D, Li H, Lu X-X, Xiao H, Ren J, Zhang F-R, et al. Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study. World J Pediatr. 2020. doi: 10.1007/s12519-020-00354-4 https://doi.org/10.1007/s12519-020-00354...
))
|
2m - 15y |
Travel history and family transmission |
NS |
Yes/03 - 10 |
Xu et al.,((2626 Xu Y, Li X, Zhu B, Liang H, Fang C, Gong Y, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 2020;26(4):502-5. doi: 10.1038/s41591-020-0817-4 https://doi.org/10.1038/s41591-020-0817-...
))
|
2 meses a 15 anos |
Community transmission |
NS |
NS |
Shi et al.,((2727 Shi Y, Wang X, Liu G, Zhu Q, Wang J, Yu H, et al. A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China. Ann Transl Med. 2020;8(5):241-241. doi: 10.21037/atm.2020.03.22 https://doi.org/10.21037/atm.2020.03.22...
))
|
7m - 11y |
Travel history and community transmission |
NS |
Yes/10 |
Su et al.,((2828 Su L, Ma X, Yu H, Zhang Z, Bian P, Han Y, et al. The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19. Emerg Micr Infect. 2020;9(1):707-13. doi: 10.1080/22221751.2020.1744483 https://doi.org/10.1080/22221751.2020.17...
))
|
11m a 9y |
Family transmission |
NS |
Yes/NS |
Tan et al.,((2929 Tan Y, Tan B, Pan J, Wu J, Zeng S, Wei H. Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China. J Clin Virol. 2020;127:104353. doi: 10.1016/j.jcv.2020.104353 https://doi.org/10.1016/j.jcv.2020.10435...
))
|
1 - 12y |
Travel history and family transmission |
NS |
Yes/20 |
Xing et al.,((3030 Xing Y-H, Ni W, Wu Q, Li W-J, Li G-J, Wang W-D, et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J Microbiol, Immunol Infect. 2020. doi: 10.1016/j.jmii.2020.03.021 https://doi.org/10.1016/j.jmii.2020.03.0...
))
|
1 -6y |
Family transmission |
NS |
Yes/NS |
Yin et al.,((3131 Yin X, Dong L, Zhang Y, Bian W, Li H. A mild type of childhood Covid-19: a case report. Radiol Infect Dis. 2020. doi: 10.1016/j.jrid.2020.03.004 https://doi.org/10.1016/j.jrid.2020.03.0...
))
|
9y |
NS |
NS |
Yes/NS |
Chen et al.,((3232 Chen J, Zhang Z-Z, Chen Y-K, Long Q-X, Tian W-G, Deng H-J, et al. The clinical and immunological features of pediatric COVID-19 patients in China. Genes Dis. 2020. doi: 10.1016/j.gendis.2020.03.008 https://doi.org/10.1016/j.gendis.2020.03...
))
|
7m - 17y |
Travel history and community transmission |
NS |
Yes/NS |
Morey-Olivé et al.,((3333 Morey-Olivé M, Espiau M, Mercadal-Hally M, Lera-Carballo E, García-Patos V. Manifestaciones cutáneas en contexto del brote actual de enfermedad por coronavirus 2019. An Pediatr. 2020. doi: 10.1016/j.anpedi.2020.04.013 https://doi.org/10.1016/j.anpedi.2020.04...
))
|
2m e 6y |
Community transmission |
Cholestatic liver disease |
Yes/NS |
Liu et al.,((3434 Liu H, Liu F, Li J, Zhang T, Wang D, Lan W. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J Infect. 2020;80(5):e7-13. doi: 10.1016/j.jinf.2020.03.007 https://doi.org/10.1016/j.jinf.2020.03.0...
))
|
11m - 9y |
Community transmission |
NS |
NS |
Chacón-Aguilar et al.,((3535 Chacón-Aguilar R, Osorio-Cámara JM, Sanjurjo-Jimenez I, González-González C, López-Carnero J, Agapito BP-M-. COVID 19: sindrome febril y clínica neurólogica en neonato. An Pediatr. 2020. doi: 10.1016/j.anpedi.2020.04.012 https://doi.org/10.1016/j.anpedi.2020.04...
))
|
26d |
NS |
NS |
Yes/06 |
Ji et al.,((3636 Ji L-N, Chao S, Wang Y-J, Li X-J, Mu X-D, Lin M-G, et al. Clinical features of pediatric patients with COVID-19: a report of two family cluster cases. World J Pediatr. 2020. doi: 10.1007/s12519-020-00356-2 https://doi.org/10.1007/s12519-020-00356...
))
|
9 e 15y |
Travel history |
No |
Yes/02 |
Cai et al.,((3737 Cai J, Xu J, Lin D, Yang Z, Xu L, Qu Z, et al. A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020;ciaa198. doi: 10.1093/cid/ciaa198 https://doi.org/10.1093/cid/ciaa198...
))
|
3m - 10y |
Family and community transmission |
NS |
Yes/NS |
Dong et al.,((3838 Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020. doi: 10.1542/peds.2020-0702 https://doi.org/10.1542/peds.2020-0702...
))
|
2 -13y |
Community transmission |
NS |
Yes/NS |
Xia et al.,((3939 Xia W, Shao J, Guo Y, Peng X, Li Z, Hu D. Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults. Pediatr Pulmonol. 2020;55(5):1169-74. doi: 10.1002/ppul.24718 https://doi.org/10.1002/ppul.24718...
))
|
1d - 14y |
Family transmission |
NS |
Yes/18 - 20 |
Zhu et al.,((4040 Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9(1):51-60. doi: 10.21037/tp.2020.02.06 https://doi.org/10.21037/tp.2020.02.06...
))
|
1 - 9d |
Community transmission |
Alteration of liver function |
Yes/NS |
Wei, et al.,((4141 Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang Z-J. Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA. 2020;323(13):1313. doi: 10.1001/jama.2020.2131 https://doi.org/10.1001/jama.2020.2131...
))
|
28d - 1y |
Family transmission |
NS |
NS |