Perfil epidemiológico de crianças e adolescentes com COVID-19: uma revisão de escopo

Bernardino, Fabiane Blanco Silva; Alencastro, Lidiane Cristina da Silva; Silva, Ronaldo Antonio da; Ribeiro, Antonia Dinágila do Nascimento; Castilho, Geovane Roberto de Campos; Gaíva, Maria Aparecida Munhoz

Fabiane Blanco Silva Bernardino

Universidade Federal de Mato Grosso. Cuiabá, Mato Grosso, Brasil.

https://orcid.org/0000-0003-0339-9451

Lidiane Cristina da Silva Alencastro

Universidade Federal de Mato Grosso. Cuiabá, Mato Grosso, Brasil.

https://orcid.org/0000-0003-3005-415X

Ronaldo Antonio da Silva

Universidade do Estado de Mato Grosso. Diamantino, Mato Grosso, Brasil.

https://orcid.org/0000-0002-1962-3182

Antonia Dinágila do Nascimento Ribeiro

Universidade Federal de Mato Grosso. Cuiabá, Mato Grosso, Brasil.

https://orcid.org/0000-0001-7852-9199

Geovane Roberto de Campos Castilho

Universidade Federal de Mato Grosso. Cuiabá, Mato Grosso, Brasil.

https://orcid.org/0000-0002-6300-1479

Maria Aparecida Munhoz Gaíva

Universidade Federal de Mato Grosso. Cuiabá, Mato Grosso, Brasil.

https://orcid.org/0000-0002-8666-9738

Autor Correspondente: Fabiane Blanco Silva Bernardino E-mail: fabianeblanco25@gmail.com

EDITOR CHEFE: Dulce Barbosa

EDITOR ASSOCIADO: Priscilla Broca

Base de dados	Estratégia de busca	Total
PubMed/ MEDLINE	"Infant, newborn" OR "Infant" OR "Children, preschool" OR "Child" OR "Adolescent" AND "Health profile" AND "Risk factors" AND "Mortality" AND "morbidity" AND "COVID-19 virus" OR "SARS-CoV-2" OR "2019-nCoV" OR "coronavirus disease 2019"	868
CINAHL	"Infant, newborn" AND "Infant" AND "Children, preschool" AND "Child" AND "Adolescent" AND "Health profile" AND "Risk factors" AND "Mortality" AND "morbidity" AND "COVID-19 virus" OR "SARS-CoV-2" OR "2019-nCoV" OR "coronavirus disease 2019"	43
Web of Science	"Infant, newborn" AND "Infant" AND "Children, preschool" AND "Child" AND "Adolescent" AND "Health profile" AND "Risk factors" AND "Mortality" AND "morbidity" AND "COVID-19 virus" OR "SARS-CoV-2" OR "2019-nCoV" OR "coronavirus disease 2019"	481
Scopus	"Infant, newborn" OR "Children, preschool" AND "Adolescent" AND "Mortality" OR "morbidity" AND "COVID-19 virus" OR "SARS-CoV-2" OR "2019-nCoV" OR "coronavirus disease 2019"	4
Science direct	"Infant, newborn" OR "Child" AND "Adolescent" AND "Mortality" AND "morbidity" AND "COVID-19 virus" OR "SARS-CoV-2" OR "2019-nCoV" OR "coronavirus disease 2019"	446
Google Acadêmico	"Child" OR "Adolescent" AND "Mortality" AND "morbidity" AND "COVID-19 virus"	59

Autores	País	Tipo de estudo	Nº participantes crianças e adolescentes
Zheng et al.,⁽⁽⁸8 Zheng F, Liao C, Fan Q, Chen H, Zhao X, Xie Z, et al. Clinical characteristics of children with Coronavirus Disease 2019 in Hubei, China. Curr Med Sci. 2020;40(2):1-6. doi: 10.1007/s11596-020-2172-6 https://doi.org/10.1007/s11596-020-2172-... ⁾⁾	China	Transversal	25 crianças
Dong et al.,⁽⁽¹¹11 Dong N, Cai J, Zhou Y, Liu J, Li F. End-stage Heart Failure with COVID-19: strong evidence of myocardial injury by 2019-nCoV. JACC: Heart Failure. 2020. doi: 10.1016/j.jchf.2020.04.001 https://doi.org/10.1016/j.jchf.2020.04.0... ⁾⁾	China	NE	01 adolescente^* Nota: ⁾
Escalera-Antezana et al.,⁽⁽¹²12 Escalera-Antezana JP, Lizon-Ferrufino NF, Maldonado-Alanoca A, Alarcón-De-la-Vega G, Alvarado-Arnez LE, Balderrama-Saavedra MA, et al. Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain. Travel Med Infect Dis. 2020. doi: 10.1016/j.tmaid.2020.101653 https://doi.org/10.1016/j.tmaid.2020.101... ⁾⁾	Bolívia	Transversal	02 adolescentes^* Nota: ⁾
Díaz et al.,⁽⁽¹³13 Díaz CA, Maestro ML, Pumarega MTM, Antón BF, Alonso CRP. Primer caso de infección neonatal por SARS-CoV-2 en España. An Pediatr. 2020;92(4):237-8. doi: 10.1016/j.anpedi.2020.03.002 https://doi.org/10.1016/j.anpedi.2020.03... ⁾⁾	Espanha	Caso clínico	01 criança
Chen et al.,⁽⁽¹⁴14 Chen C, Gao G, Xu Y, Pu L, Wang Q, Wang L, et al. SARS-CoV-2-Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19. Ann Intern Med. 2020;M20-0991. doi: 10.7326/M20-0991 https://doi.org/10.7326/M20-0991... ⁾⁾	China	NE	04 crianças^* Nota: ⁾
Xiang et al.,⁽⁽¹⁵15 Xiang M, Liang S, Zhang Y, Zhang X, Gai Z, Zhang Z. Do children need a longer time to shed SARS-CoV-2 in stool than adults? J Microbiol, Immunol Infect. 2020. doi: 10.1016/j.jmii.2020.03.010 https://doi.org/10.1016/j.jmii.2020.03.0... ⁾⁾	China	NE	06 crianças^* Nota: ⁾
Peng e Zhang⁽⁽¹⁶16 Peng A, Zhang M. Novel coronavirus SARS-CoV-2: familial spread resulting in COVID-19 pneumonia in a pediatric patient. Diagn Interv Radiol. 2020;26(3):262-3. doi: 10.5152/dir.2020.20157 https://doi.org/10.5152/dir.2020.20157... ⁾⁾	China	NE	01 criança
Park et al.⁽⁽¹⁷17 Park JY, Han MS, Park KU, Kim JY, Choi EH. First Pediatric Case of Coronavirus Disease 2019 in Korea. J Korean Med Sci. 2020;35(11):e124. doi: 10.3346/jkms.2020.35.e124 https://doi.org/10.3346/jkms.2020.35.e12... ⁾⁾	Coreia	Caso clínico	01 criança
Lu et al.⁽⁽¹⁸18 Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. New England J Med. 2020;382(17):1663-5. doi: 10.1056/NEJMc2005073 https://doi.org/10.1056/NEJMc2005073... ⁾⁾	China	NE	171 crianças e adolescentes^* Nota: ⁾
Ng et al.⁽⁽¹⁹19 Ng O-T, Marimuthu K, Chia P-Y, Koh V, Chiew CJ, De Wang L, et al. SARS-CoV-2 Infection among Travelers Returning from Wuhan, China. N Engl J Med. 2020;382(15):1476-8. doi: 10.1056/NEJMc2003100 https://doi.org/10.1056/NEJMc2003100... ⁾⁾	China	NE	01 adolescente^* Nota: ⁾
Wang et al.⁽⁽²⁰20 Wang S, Guo L, Chen L, Liu W, Cao Y, Zhang J, et al. A case report of neonatal COVID-19 infection in China. Clin Infect Dis. 2020. doi: 10.1093/cid/ciaa225 https://doi.org/10.1093/cid/ciaa225... ⁾⁾	China	Caso clínico	01 criança
Cao et al.⁽⁽²¹21 Cao Q, Chen Y-C, Chen C-L, Chiu C-H. SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics. J Formosan Med Assoc. 2020;119(3):670-3. doi: 10.1016/j.jfma.2020.02.009 https://doi.org/10.1016/j.jfma.2020.02.0... ⁾⁾	China	NE	02 crianças
Guan et al.⁽⁽²²22 Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708-20. doi: 10.1056/NEJMoa2002032 https://doi.org/10.1056/NEJMoa2002032... ⁾⁾	China	Transversal	09 crianças e adolescentes^* Nota: ⁾
Mansour et al.,⁽⁽²³23 Mansour A, Atoui R, Kanso K, Mohsen R, Fares Y, Fares J. First Case of an Infant with COVID-19 in the Middle East. Cureus. 2020. doi: 10.7759/cureus.7520 https://doi.org/10.7759/cureus.7520... ⁾⁾	Líbano	Caso clínico	01 criança
Pan et al.⁽⁽²⁴24 Pan X, Chen D, Xia Y, Wu X, Li T, Ou X, et al. Asymptomatic cases in a family cluster with SARS-CoV-2 infection. Lancet Infect Dis. 2020;20(4):410-1. doi: 10.1016/S1473-3099(20)30114-6 https://doi.org/10.1016/S1473-3099(20)30... ⁾⁾	China	Caso clínico	01 criança^* Nota: ⁾
Sun et al.⁽⁽²⁵25 Sun D, Li H, Lu X-X, Xiao H, Ren J, Zhang F-R, et al. Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study. World J Pediatr. 2020. doi: 10.1007/s12519-020-00354-4 https://doi.org/10.1007/s12519-020-00354... ⁾⁾	China	Transversal	08 crianças e adolescentes
Xu et al.,⁽⁽²⁶26 Xu Y, Li X, Zhu B, Liang H, Fang C, Gong Y, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 2020;26(4):502-5. doi: 10.1038/s41591-020-0817-4 https://doi.org/10.1038/s41591-020-0817-... ⁾⁾	China	Transversal	10 crianças e adolescentes^* Nota: ⁾
Shi et al.,⁽⁽²⁷27 Shi Y, Wang X, Liu G, Zhu Q, Wang J, Yu H, et al. A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China. Ann Transl Med. 2020;8(5):241-241. doi: 10.21037/atm.2020.03.22 https://doi.org/10.21037/atm.2020.03.22... ⁾⁾	China	Transversal	10 crianças e adolescentes^* Nota: ⁾
Su et al.,⁽⁽²⁸28 Su L, Ma X, Yu H, Zhang Z, Bian P, Han Y, et al. The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19. Emerg Micr Infect. 2020;9(1):707-13. doi: 10.1080/22221751.2020.1744483 https://doi.org/10.1080/22221751.2020.17... ⁾⁾	China	Transversal	09 crianças^* Nota: ⁾
Tan et al.,⁽⁽²⁹29 Tan Y, Tan B, Pan J, Wu J, Zeng S, Wei H. Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China. J Clin Virol. 2020;127:104353. doi: 10.1016/j.jcv.2020.104353 https://doi.org/10.1016/j.jcv.2020.10435... ⁾⁾	China	Transversal	10 crianças e adolescentes
Xing et al.,⁽⁽³⁰30 Xing Y-H, Ni W, Wu Q, Li W-J, Li G-J, Wang W-D, et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J Microbiol, Immunol Infect. 2020. doi: 10.1016/j.jmii.2020.03.021 https://doi.org/10.1016/j.jmii.2020.03.0... ⁾⁾	China	Transversal	3 crianças
Yin et al.,⁽⁽³¹31 Yin X, Dong L, Zhang Y, Bian W, Li H. A mild type of childhood Covid-19: a case report. Radiol Infect Dis. 2020. doi: 10.1016/j.jrid.2020.03.004 https://doi.org/10.1016/j.jrid.2020.03.0... ⁾⁾	China	Transversal	1 criança
Chen et al.,⁽⁽³²32 Chen J, Zhang Z-Z, Chen Y-K, Long Q-X, Tian W-G, Deng H-J, et al. The clinical and immunological features of pediatric COVID-19 patients in China. Genes Dis. 2020. doi: 10.1016/j.gendis.2020.03.008 https://doi.org/10.1016/j.gendis.2020.03... ⁾⁾	China	Transversal	12 crianças e adolescentes^* Nota: ⁾
Morey-Olivé et al.,⁽⁽³³33 Morey-Olivé M, Espiau M, Mercadal-Hally M, Lera-Carballo E, García-Patos V. Manifestaciones cutáneas en contexto del brote actual de enfermedad por coronavirus 2019. An Pediatr. 2020. doi: 10.1016/j.anpedi.2020.04.013 https://doi.org/10.1016/j.anpedi.2020.04... ⁾⁾	Espanha	Casos clínicos	2 crianças
Liu et al.,⁽⁽³⁴34 Liu H, Liu F, Li J, Zhang T, Wang D, Lan W. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J Infect. 2020;80(5):e7-13. doi: 10.1016/j.jinf.2020.03.007 https://doi.org/10.1016/j.jinf.2020.03.0... ⁾⁾	China	Transversal	04 crianças^* Nota: ⁾
Chacón-Aguilar et al.,⁽⁽³⁵35 Chacón-Aguilar R, Osorio-Cámara JM, Sanjurjo-Jimenez I, González-González C, López-Carnero J, Agapito BP-M-. COVID 19: sindrome febril y clínica neurólogica en neonato. An Pediatr. 2020. doi: 10.1016/j.anpedi.2020.04.012 https://doi.org/10.1016/j.anpedi.2020.04... ⁾⁾	Espanha	Caso clínico	01 criança
Ji et al.,⁽⁽³⁶36 Ji L-N, Chao S, Wang Y-J, Li X-J, Mu X-D, Lin M-G, et al. Clinical features of pediatric patients with COVID-19: a report of two family cluster cases. World J Pediatr. 2020. doi: 10.1007/s12519-020-00356-2 https://doi.org/10.1007/s12519-020-00356... ⁾⁾	China	Casos clínicos	01 criança e 01 adolescente
Cai et al.,⁽⁽³⁷37 Cai J, Xu J, Lin D, Yang Z, Xu L, Qu Z, et al. A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020;ciaa198. doi: 10.1093/cid/ciaa198 https://doi.org/10.1093/cid/ciaa198... ⁾⁾	China	NE	10 crianças e adolescentes
Dong et al.,⁽⁽³⁸38 Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020. doi: 10.1542/peds.2020-0702 https://doi.org/10.1542/peds.2020-0702... ⁾⁾	China	NE	2135 crianças e adolescentes
Xia et al.,⁽⁽³⁹39 Xia W, Shao J, Guo Y, Peng X, Li Z, Hu D. Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults. Pediatr Pulmonol. 2020;55(5):1169-74. doi: 10.1002/ppul.24718 https://doi.org/10.1002/ppul.24718... ⁾⁾	China	NE	20 crianças e adolescentes
Zhu et al.,⁽⁽⁴⁰40 Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9(1):51-60. doi: 10.21037/tp.2020.02.06 https://doi.org/10.21037/tp.2020.02.06... ⁾⁾	China	Transversal	10 crianças
Wei, et al.,⁽⁽⁴¹41 Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang Z-J. Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA. 2020;323(13):1313. doi: 10.1001/jama.2020.2131 https://doi.org/10.1001/jama.2020.2131... ⁾⁾	China	Transversal	09 crianças

Autores	Faixa etária	Provável contaminação da doença	Doença/Condição Pré-existente	Internação/ Tempo ⁽dias⁾
Zheng et al.,⁽⁽⁸8 Zheng F, Liao C, Fan Q, Chen H, Zhao X, Xie Z, et al. Clinical characteristics of children with Coronavirus Disease 2019 in Hubei, China. Curr Med Sci. 2020;40(2):1-6. doi: 10.1007/s11596-020-2172-6 https://doi.org/10.1007/s11596-020-2172-... ⁾⁾	0 - 6a	Histórico de viagem	Suspeita de doenças metabólicas hereditárias e cardiopatias congênitas	Sim/ 10
Dong et al.,⁽⁽¹¹11 Dong N, Cai J, Zhou Y, Liu J, Li F. End-stage Heart Failure with COVID-19: strong evidence of myocardial injury by 2019-nCoV. JACC: Heart Failure. 2020. doi: 10.1016/j.jchf.2020.04.001 https://doi.org/10.1016/j.jchf.2020.04.0... ⁾⁾	11a	NE	Insuficiência cardíaca	Sim/ NE
Escalera-Antezana et al.,⁽⁽¹²12 Escalera-Antezana JP, Lizon-Ferrufino NF, Maldonado-Alanoca A, Alarcón-De-la-Vega G, Alvarado-Arnez LE, Balderrama-Saavedra MA, et al. Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain. Travel Med Infect Dis. 2020. doi: 10.1016/j.tmaid.2020.101653 https://doi.org/10.1016/j.tmaid.2020.101... ⁾⁾	13 e 18a	Transmissão familiar e NE	Não	Não
Díaz et al.,⁽⁽¹³13 Díaz CA, Maestro ML, Pumarega MTM, Antón BF, Alonso CRP. Primer caso de infección neonatal por SARS-CoV-2 en España. An Pediatr. 2020;92(4):237-8. doi: 10.1016/j.anpedi.2020.03.002 https://doi.org/10.1016/j.anpedi.2020.03... ⁾⁾	8d	Transmissão comunitária	Prematuridade	Sim/ 13
Chen et al.,⁽⁽¹⁴14 Chen C, Gao G, Xu Y, Pu L, Wang Q, Wang L, et al. SARS-CoV-2-Positive Sputum and Feces After Conversion of Pharyngeal Samples in Patients With COVID-19. Ann Intern Med. 2020;M20-0991. doi: 10.7326/M20-0991 https://doi.org/10.7326/M20-0991... ⁾⁾	2 - 10a	Transmissão comunitária	Não	Sim/ NE
Xiang et al.,⁽⁽¹⁵15 Xiang M, Liang S, Zhang Y, Zhang X, Gai Z, Zhang Z. Do children need a longer time to shed SARS-CoV-2 in stool than adults? J Microbiol, Immunol Infect. 2020. doi: 10.1016/j.jmii.2020.03.010 https://doi.org/10.1016/j.jmii.2020.03.0... ⁾⁾	11m -9a	Transmissão familiar	NE	Sim/ NE
Peng e Zhang⁽⁽¹⁶16 Peng A, Zhang M. Novel coronavirus SARS-CoV-2: familial spread resulting in COVID-19 pneumonia in a pediatric patient. Diagn Interv Radiol. 2020;26(3):262-3. doi: 10.5152/dir.2020.20157 https://doi.org/10.5152/dir.2020.20157... ⁾⁾	03a	Transmissão familiar	Não	NE
Park et al.⁽⁽¹⁷17 Park JY, Han MS, Park KU, Kim JY, Choi EH. First Pediatric Case of Coronavirus Disease 2019 in Korea. J Korean Med Sci. 2020;35(11):e124. doi: 10.3346/jkms.2020.35.e124 https://doi.org/10.3346/jkms.2020.35.e12... ⁾⁾	10a	Transmissão familiar	Não	Sim/ 15
Lu et al.⁽⁽¹⁸18 Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. New England J Med. 2020;382(17):1663-5. doi: 10.1056/NEJMc2005073 https://doi.org/10.1056/NEJMc2005073... ⁾⁾	0 - 16a	Transmissão familiar	Hidronefrose e Leucemia	NE
Ng et al.⁽⁽¹⁹19 Ng O-T, Marimuthu K, Chia P-Y, Koh V, Chiew CJ, De Wang L, et al. SARS-CoV-2 Infection among Travelers Returning from Wuhan, China. N Engl J Med. 2020;382(15):1476-8. doi: 10.1056/NEJMc2003100 https://doi.org/10.1056/NEJMc2003100... ⁾⁾	17a	Transmissão comunitária	Não	Não
Wang et al.⁽⁽²⁰20 Wang S, Guo L, Chen L, Liu W, Cao Y, Zhang J, et al. A case report of neonatal COVID-19 infection in China. Clin Infect Dis. 2020. doi: 10.1093/cid/ciaa225 https://doi.org/10.1093/cid/ciaa225... ⁾⁾	36h	Transmissão vertical	Não	Sim/ 18
Cao et al.⁽⁽²¹21 Cao Q, Chen Y-C, Chen C-L, Chiu C-H. SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics. J Formosan Med Assoc. 2020;119(3):670-3. doi: 10.1016/j.jfma.2020.02.009 https://doi.org/10.1016/j.jfma.2020.02.0... ⁾⁾	03m	Transmissão familiar	Não	Sim/ 15
Guan et al.⁽⁽²²22 Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708-20. doi: 10.1056/NEJMoa2002032 https://doi.org/10.1056/NEJMoa2002032... ⁾⁾	0 - 15a	Transmissão comunitária	Não	NE
Mansour et al.,⁽⁽²³23 Mansour A, Atoui R, Kanso K, Mohsen R, Fares Y, Fares J. First Case of an Infant with COVID-19 in the Middle East. Cureus. 2020. doi: 10.7759/cureus.7520 https://doi.org/10.7759/cureus.7520... ⁾⁾	16m	Transmissão familiar	Infecção p/ Streptococcus pneumoniae	Sim/ NE
Pan et al.⁽⁽²⁴24 Pan X, Chen D, Xia Y, Wu X, Li T, Ou X, et al. Asymptomatic cases in a family cluster with SARS-CoV-2 infection. Lancet Infect Dis. 2020;20(4):410-1. doi: 10.1016/S1473-3099(20)30114-6 https://doi.org/10.1016/S1473-3099(20)30... ⁾⁾	03a	Transmissão familiar	Não	Sim/ 03
Sun et al.⁽⁽²⁵25 Sun D, Li H, Lu X-X, Xiao H, Ren J, Zhang F-R, et al. Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study. World J Pediatr. 2020. doi: 10.1007/s12519-020-00354-4 https://doi.org/10.1007/s12519-020-00354... ⁾⁾	2m - 15a	Histórico de viagem e transmissão familiar	NE	Sim/ 03 - 10
Xu et al.,⁽⁽²⁶26 Xu Y, Li X, Zhu B, Liang H, Fang C, Gong Y, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 2020;26(4):502-5. doi: 10.1038/s41591-020-0817-4 https://doi.org/10.1038/s41591-020-0817-... ⁾⁾	2 meses a 15 anos	Transmissão comunitária	NE	NE
Shi et al.,⁽⁽²⁷27 Shi Y, Wang X, Liu G, Zhu Q, Wang J, Yu H, et al. A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China. Ann Transl Med. 2020;8(5):241-241. doi: 10.21037/atm.2020.03.22 https://doi.org/10.21037/atm.2020.03.22... ⁾⁾	7m - 11a	Histórico de viagem e transmissão comunitária	NE	Sim/10
Su et al.,⁽⁽²⁸28 Su L, Ma X, Yu H, Zhang Z, Bian P, Han Y, et al. The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19. Emerg Micr Infect. 2020;9(1):707-13. doi: 10.1080/22221751.2020.1744483 https://doi.org/10.1080/22221751.2020.17... ⁾⁾	11m a 9a	Transmissão familiar	NE	Sim/ NE
Tan et al.,⁽⁽²⁹29 Tan Y, Tan B, Pan J, Wu J, Zeng S, Wei H. Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China. J Clin Virol. 2020;127:104353. doi: 10.1016/j.jcv.2020.104353 https://doi.org/10.1016/j.jcv.2020.10435... ⁾⁾	1 - 12a	Histórico de viagem e transmissão familiar	NE	Sim/ 20
Xing et al.,⁽⁽³⁰30 Xing Y-H, Ni W, Wu Q, Li W-J, Li G-J, Wang W-D, et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J Microbiol, Immunol Infect. 2020. doi: 10.1016/j.jmii.2020.03.021 https://doi.org/10.1016/j.jmii.2020.03.0... ⁾⁾	1 -6a	Transmissão familiar	NE	Sim/ NE
Yin et al.,⁽⁽³¹31 Yin X, Dong L, Zhang Y, Bian W, Li H. A mild type of childhood Covid-19: a case report. Radiol Infect Dis. 2020. doi: 10.1016/j.jrid.2020.03.004 https://doi.org/10.1016/j.jrid.2020.03.0... ⁾⁾	9a	NE	NE	Sim/ NE
Chen et al.,⁽⁽³²32 Chen J, Zhang Z-Z, Chen Y-K, Long Q-X, Tian W-G, Deng H-J, et al. The clinical and immunological features of pediatric COVID-19 patients in China. Genes Dis. 2020. doi: 10.1016/j.gendis.2020.03.008 https://doi.org/10.1016/j.gendis.2020.03... ⁾⁾	7m - 17a	Histórico de viagem e transmissão comunitária	NE	Sim/ NE
Morey-Olivé et al.,⁽⁽³³33 Morey-Olivé M, Espiau M, Mercadal-Hally M, Lera-Carballo E, García-Patos V. Manifestaciones cutáneas en contexto del brote actual de enfermedad por coronavirus 2019. An Pediatr. 2020. doi: 10.1016/j.anpedi.2020.04.013 https://doi.org/10.1016/j.anpedi.2020.04... ⁾⁾	2m e 6a	Transmissão comunitária	Doença hepática colestática	Sim/ NE
Liu et al.,⁽⁽³⁴34 Liu H, Liu F, Li J, Zhang T, Wang D, Lan W. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J Infect. 2020;80(5):e7-13. doi: 10.1016/j.jinf.2020.03.007 https://doi.org/10.1016/j.jinf.2020.03.0... ⁾⁾	11m - 9a	Transmissão comunitária	NE	NE
Chacón-Aguilar et al.,⁽⁽³⁵35 Chacón-Aguilar R, Osorio-Cámara JM, Sanjurjo-Jimenez I, González-González C, López-Carnero J, Agapito BP-M-. COVID 19: sindrome febril y clínica neurólogica en neonato. An Pediatr. 2020. doi: 10.1016/j.anpedi.2020.04.012 https://doi.org/10.1016/j.anpedi.2020.04... ⁾⁾	26d	NE	NE	Sim/ 06
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[1] Autor Correspondente: Fabiane Blanco Silva Bernardino E-mail: fabianeblanco25@gmail.com

Brasil

Brasil

Perfil epidemiológico de crianças e adolescentes com COVID-19: uma revisão de escopo

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